The Development of An Animal-Specific Metagenomic Sequencing Pipeline to Increase Our Understanding of the Microbiome
Time: 9:30 am
Details:
- The lack of complete animal-specific databases for microbiome studies
has limited our understanding of the animal microbiome - Diversigen has developed MetaGene™ Mouse, a mouse-specific shotgun
metagenomic sequencing pipeline and a mouse-specific microbiome
database that significantly improve the detection and identification of
bacterial species and strains unique to mice, outperforming publically
available databases - MetaGene™ Mouse increases the overall median mapping rate from 12%
to 45%. Furthermore, it increases the understanding of the microbiome
function thanks to a 5-fold increase in functional mapping rate based on
our mouse-specific database. - The approach we took with the mouse microbiome can be applied to any
animal species, including companion, and production, to facilitate a better
understanding of each animal’s unique microbiome
