Conference Day One

8:15 am Registration & Coffee Morning

8:50 am Chairs Opening Comments

Understanding an Animal’s Gut Microbiome & Uncovered Mechanisms of Action

9:00 am An Animal’s Immune System

Synopsis

• Understand how the microbiome influences immune development
• Analyze ways the microbiome trains the immune system
• Discuss ways the microbiome can inhibit the immune system

9:30 am Gut Microbiome Modulation in Farm Animals: A Critical View

  • Marcos Rostagno Science, Innovation, Technical Services - Poultry and Swine Health & Nutrition, Phytobiotics North America, LLC

Synopsis

• The complexity of defining gut health in farm animals
• How does the gut microbiome fit in?
• Gut microbiome modulation: Where are we and where are we going?

10:00 am Early Microbiome Development in Swine Production Systems

  • Andres Gomez Assistant Professor, University of Minnesota-Twin Cities

Synopsis

• Early life events are key in shaping microbiome development in the new born
• The effects of these events may be long lasting (e.g. beyond weaning)
• Manipulation of microbiomes at early life stages may be promising in favourably modulating productive and immune performance later in life

10:30 am Structured Networking

Diagnostics, Biomarkers & Clinical Endpoints: Ensuring Efficacy is a Priority

11:00 am The Development of An Animal-Specific Metagenomic Sequencing Pipeline to Increase Our Understanding of the Microbiome

Synopsis

• The lack of complete animal-specific databases for microbiome studies has limited our understanding of the animal microbiome
• Diversigen has developed MetaGene™ Mouse, a mouse-specific shotgun metagenomic sequencing pipeline and a mouse-specific microbiome database that significantly improve the detection and identification of bacterial species and strains unique to mice, outperforming publically
available databases
• MetaGene™ Mouse increases the overall median mapping rate from 12% to 45%. Furthermore, it increases the understanding of the microbiome function thanks to a 5-fold increase in functional mapping rate based on our mouse-specific database.
• The approach we took with the mouse microbiome can be applied to any animal species, including companion, and production, to facilitate a better understanding of each animal’s unique microbiome

11:10 am The Effect of Dietary Additives on Intestinal Metabolites

  • Xandra Smith Director of Innovation and Product Development, Arm & Hammer Animal & Food Production

Synopsis

• Intestinal metabolites are altered by dietary treatments such as antibiotics and probiotics
• What role do these altered metabolites play in promoting host health?
• An understanding of microbiota-derived metabolites may lead to novel treatments

11:40 am Roundtable Discussion:

Synopsis

• The revolution of rrobiotics in dogs & cats
• The microbiome as a diagnostic tool
• Understanding the mechanisms of therapeutic & nutritional products
• Novel successful treatment potential

12:10 pm Lunch Break & Networking

Moving From Correlation to Causation – Unearthing the Underlying Mechanisms of Nutritional Products

1:30 pm Enzymatic Solutions for Dog Teeth Cleaning

Synopsis

• Enzymatic solutions for dog teeth cleaning
• Use of Bacillus spores in animal feed to increase body weight gain in commercial poultry
• The role of the gut microbiome plays in affecting the gut-brain axis in dogs

2:00 pm Superculture Ingredients: New Natural Ingredients for Animal Health & Beyond

Synopsis

• Superculture ingredients are natural & defensible actives based on combinations of microbial cultures (non GMO)
• Significant gaps in animal products today across product performance use of artificial/chemical ingredients
• Shifting from off-the shelf solutions allows for exciting new products

2:30 pm Ileal and Cecal Microbiota Profiles of 1940s & 2016 White Leghorns fed Representative Diets

  • Dannica Wall Research Specialist, Poultry Science Professional, North Carolina State University

Synopsis

• Identify differences between the microbiome composition of the ileum and ceca
• Highlight the importance of the observed microbiome composition
• Genetic effects that contribute to microbiome composition of the ileum and ceca

3:00 pm Afternoon Networking & Refreshments

3:30 pm PANEL: Transforming Product Development Through Data-Driven Approaches

  • Xandra Smith Director of Innovation and Product Development, Arm & Hammer Animal & Food Production
  • Jeffrey W. Hall Director of R&D, Vetanco USA
  • Prof Mick Watson Personal chair in bioinformatics and computational biology Director of Genomics at Edinburgh, The Roslin Institute and Royal(Dick) School of Veterinary Studies University of Edinburgh
  • Holly Ganz CSO, AnimalBiome

4:00 pm Rumen Contents Dosing During Calf Development & its Impact on Downstream Milk Production

  • Garret Suen Associate Professor of Bacteriology, University of Wisconsin-Madison

Synopsis

• Removal of calves from their dams after birth may impact the development of the ruminal microbiome
• This presents an opportunity to influence the development of adult microbiome during calf development.
• Rumen contents dosing in calves impacts ruminal microbiome development but does not appear to influence milk production

4:30 pm Direct-fed Microbials, Antibiotics and Their Impact on the Broiler Microbiome

Synopsis

• How DFMs influence the intestinal bacterial-biome development
• How AGPs influence the intestinal bacterial-biome development
• Replacement of AGPs with DFMs

5:00 pm Close of Day One